"Do not try to make George's marvelous medicine yourselves at home. It could be dangerous. George is alone in the house with Grandma. The most horrid, grizzly old grunion of a grandma ever. She needs something stronger than her usual medicine to cure her chronic grouchiness. A special grandma medicine, a remedy for everything. And George knows just what to put into it. Grandma's in for the surprise of her life - and so is George, when he sees the results of his mixture!" -- inside front cover flap.